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“The science of today is the technology of tomorrow”
- Edward Teller -


Journal Publications (last 5 yrs)

  1. Giannitelli, S. M., Limiti, E., Mozetic, P., Pinelli, F., Han, X., Abbruzzese, F., ... & Rainer, A. (2022). Droplet-based microfluidic synthesis of nanogels for controlled drug delivery: tailoring nanomaterial properties via pneumatically actuated flow-focusing junction. Nanoscale, 14(31), 11415-11428.

  2. E. Limiti, P. Mozetic, S. M. Giannitelli, F. Pinelli, X. Han, D. Del Rio, F. Abbruzzese, F. Basoli, L. Rosanò, S. Scialla, M. Trombetta, G. Gigli, Z. J. Zhang, E. Mauri and A. Rainer, "Hyaluronic Acid–Polyethyleneimine Nanogels for Controlled Drug Delivery in Cancer Treatment." ACS Applied Nano Materials 5.4 (2022): 5544-5557

  3. E. Mauri, M. Gori, S.M. Giannitelli, A. Zancla, P. Mozetic, F. Abbruzzese, N. Merendino, G. Gigli, F. Rossi, M. Trombetta, A. Rainer. Nano-encapsulation of hydroxytyrosol into formulated nanogels improves therapeutic effects against hepatic steatosis: An in vitro study. Mater Sci Eng C 124 (2021) 112080. doi: 10.1016/j.msec.2021.112080.

  4. E. Mauri, S.M. Giannitelli, M. Trombetta, A. Rainer. Synthesis of nanogels: current trends and future outlook. Gels 7 (2021) 38. doi: 10.3390/gels7020036.

  5. M. Costantini, S. Testa, E. Fornetti, C. Fuoco, C. Sanchez Riera, M. Nie, S. Bernardini, A. Rainer, J. Baldi, C. Zoccali, R. Biagini, L. Castagnoli, L. Vitiello, B. Blaauw, D. Seliktar, W. Święszkowski, P. Garstecki, S. Takeuchi, G. Cesareni, S. Cannata, C. Gargioli. Biofabricating murine and human myo‐substitutes for rapid volumetric muscle loss restoration. EMBO Mol Med 13 (2021) e12778. doi: 10.15252/emmm.202012778.

  6. A.R. Perestrelo, A.C. Silva, J. Oliver-De La Cruz, F. Martino, V. Horvath, G. Caluori, O. Polanský, V. Vinarsky, G. Azzato, G. de Marco, V. Zampachova, P. Skladal, S. Pagliari, A. Rainer, P. Pinto-do-Ó, A. Caravella, K. Koci, D.S. Nascimento, G. Forte. Multiscale Analysis of Extracellular Matrix Remodeling in the Failing Heart. Circulation Research 128 (2021) 24-38.  doi: 10.1161/CIRCRESAHA.120.317685.

  7. M. Gori, S.M. Giannitelli, A. Zancla, P. Mozetic, M. Trombetta, A. Rainer. Quercetin and hydroxytyrosol as modulators of hepatic steatosis: A NAFLD‐on‐a‐chip study. Biotechnology and Bioengineering. 118 (2021) 142-152. doi:  10.1002/bit.27557.

  8. S. Pagliari, V. Vinarsky, F. Martino, A.R. Perestrelo, J. Oliver-De La Cruz, G. Caluori, J. Vrbsky, P. Mozetic, A. Pompeiano, A. Zancla, S.G. Ranjani, P. Skladal, D. Kytyr, Z. Zdráhal, G. Grassi, M. Sampaolesi, A. Rainer, G. Forte. YAP–TEAD1 control of cytoskeleton dynamics and intracellular tension guides human pluripotent stem cell mesoderm specification. Cell Death & Differentiation 28 (2021) 1193–1207  doi: 10.1038/s41418-020-00643-5.

  9. M. Gori, S.M. Giannitelli, M. Torre, P. Mozetic, F. Abbruzzese, M. Trombetta, E. Traversa, L. Moroni, A. Rainer. Biofabrication of hepatic constructs by 3D bioprinting of a cell-laden thermogel: an effective tool to assess drug-induced hepatotoxic response. Adv Healthcare Mater 9(21) (2020) 2001163. doi: 10.1002/adhm.202001163.

  10. E. Mauri, A. Salvati, A. Cataldo, P. Mozetic, F. Basoli, F. Abbruzzese, M. Trombetta, S. Bellucci, A. Rainer. Graphene-laden hydrogels: a strategy for thermally triggered drug delivery. Mater Sci Eng C. (2020). doi: 10.1016/j.msec.2020.111353.

  11. S. Scarpino, S. Taccogna, G. Pepe, E. Papini, M. D’Angelo, F. Cascone, D. Nicoletti, R. Guglielmi, A. Palermo, M. Trombetta, A. Rainer, C. Taffon, A. Crescenzi. Morphological and molecular assessment in thyroid cytology using cell-capturing scaffolds. Horm Metabol Res. (2020) doi: 10.1055/a-1157-6419. 

  12. M. Gori, A. Altomare, S. Cocca, E. Solida, M. Ribolsi, S. Carotti, A. Rainer, M. Francesconi, S. Morini, M. Cicala, M.P.L. Guarino, Palmitic acid affects intestinal epithelial barrier integrity and permeability in vitro, Antioxidants 9 (2020) 417. doi:10.3390/antiox9050417.

  13. S. Lorenzetti, G. Aquilina, F. Caloni, E.M. Coccia, P. Cozzini, G. Cruciani, A. Fouassier, A. Gissi, L. Goracci, T. Heinonen, P. Hubert, F. Madia, F. Nevelli, A. Rainer, C. Rovida, A. Vitale, I. De Angelis. Non animal methodologies (NAMs): Research, testing, assessment and applications - ecopa Symposium 2019. ALTEX 37(2) (2020) 317. doi:10.14573/altex.2003041​​

  14. E. Mauri, A. Rossetti, P. Mozetic, C. Schiavon, A. Sacchetti, A. Rainer, F. Rossi, Ester coupling of ibuprofen in hydrogel matrix: a facile one-step strategy for controlled anti-inflammatory drug release. Eur J Pharm Biopharm 146 (2020) 143. doi:10.1016/j.ejpb.2019.11.002

  15. E. Mauri, P. Veglianese, S. Papa, A. Rossetti, M. De Paola, A. Mariani, Z. Posel, P. Posocco, A. Sacchetti, F. Rossi, Effects of primary amine-based coatings on microglia internalization of nanogels, Colloids Surf B - in press. doi:10.1016/j.colsurfb.2019.110574

  16. E. Mauri, D. Naso, A. Rossetti, E. Borghi, E. Ottaviano E., G. Griffini, M. Masi, A. Sacchetti, F. Rossi, Design of polymer-based antimicrobial hydrogels through physico-chemical transition, Mater Sci Eng C 103 (2019), 109791. doi:10.1016/j.msec.2019.109791

  17. E. Nocita, A. Del Giovane, M. Tiberi, L. Boccuni, D. Fiorelli, C. Sposato, E. Romano, F. Basoli, M. Trombetta, A. Rainer, E. Traversa, A. Ragnini-Wilson. EGFR/ErbB Inhibition Promotes OPC Maturation up to Axon Engagement by Co-Regulating PIP2 and MBP. Cells. 8 (2019) 844. doi: 10.3390/cells8080844.

  18. E. Mauri, G. Perale, F. Rossi, Nanogel functionalization: a versatile approach to meet the challenges of drug and gene delivery, ACS Appl Nano Mater 1 (2018), 6525-6541. doi:10.1021/acsanm.8b01686

  19. M. Costantini, J. Guzowski P.J. Żuk, P. Mozetic, S. De Panfilis, J. Jaroszewicz, et al. Electric Field Assisted Microfluidic Platform for Generation of Tailorable Porous Microbeads as Cell Carriers for Tissue Engineering, Adv. Funct. Mater. (2018). doi:10.1002/adfm.201800874.

  20. F. R. Bertani, P. Mozetic, M. Fioramonti, M. Iuliani, G. Ribelli, F. Pantano, D. Santini, G. Tonini, M. Trombetta, L. Businaro, S. Selci, A. Rainer, Classification of M1/M2-polarized human macrophages by label-free hyperspectral reflectance confocal microscopy and multivariate analysis, Sci. Rep.,7 (2017) 8965. doi:10.1038/s41598-017-08121-8. 

  21. A. Gizzi, S.M. Giannitelli, M. Trombetta, C. Cherubini, S. Filippi, A. De Ninno, L. Businaro, A. Gerardino, A. Rainer, Computationally Informed Design of a Multi-Axial Actuated Microfluidic Chip Device, Sci. Rep. 7 (2017) 5489.  

  22. S. Testa, M. Costantini, E. Fornetti, S. Bernardini, M. Trombetta, D. Seliktar, et al., Combination of biochemical and mechanical cues for tendon tissue engineering, J. Cell. Mol. Med. (2017). doi:10.1111/jcmm.13186.

  23. C. Spadaccio, F. Nappi, F. De Marco, P. Sedati, C. Taffon, A. Nenna, et al., Implantation of a Poly-L-Lactide GCSF-Functionalized Scaffold in a Model of Chronic Myocardial Infarction, J. Cardiovasc. Transl. Res. 10 (2017) 47–65. doi:10.1007/s12265-016-9718-9.

  24. P. Mozetic, S.M. Giannitelli, M. Gori, M. Trombetta, A. Rainer, Engineering muscle cell alignment through 3D bioprinting, J. Biomed. Mater. Res. A. (2017). doi:10.1002/jbm.a.36117.

  25. V. Lucarini, C. Buccione, G. Ziccheddu, F. Peschiaroli, P. Sestili, R. Puglisi, et al., Combining Type I Interferons and 5-Aza-2’-Deoxycitidine to Improve Anti-Tumor Response against Melanoma, J. Invest. Dermatol. 137 (2017) 159–169. doi:10.1016/j.jid.2016.08.024.

  26. M. Costantini, S. Testa, P. Mozetic, A. Barbetta, C. Fuoco, E. Fornetti, et al., Microfluidic-enhanced 3D bioprinting of aligned myoblast-laden hydrogels leads to functionally organized myofibers in vitro and in vivo, Biomaterials. 131 (2017) 98–110. doi:10.1016/j.biomaterials.2017.03.026.

  27. M. Costantini, S. Testa, E. Fornetti, A. Barbetta, M. Trombetta, S.M. Cannata, et al., Engineering Muscle Networks in 3D Gelatin Methacryloyl Hydrogels: Influence of Mechanical Stiffness and Geometrical Confinement, Front. Bioeng. Biotechnol. 5 (2017) 22. doi:10.3389/fbioe.2017.00022.

  28. N. Celikkin, C. Rinoldi, M. Costantini, M. Trombetta, A. Rainer, W. Święszkowski, Naturally derived proteins and glycosaminoglycan scaffolds for tissue engineering applications, Mater. Sci. Eng. C. 78 (2017) 1277–1299. doi:10.1016/j.msec.2017.04.016.

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